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Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein.
The expression and incorporation of retroviral enzymes into virions in the form of Gag/Pol precursor polyproteins is believed to be important for the assembly of infectious viral particles. HIV-1 encodes a 160 kDa Gag/Pol precursor that includes Gag, protease (PR), reverse transcriptase (RT) and int...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170145/ https://ncbi.nlm.nih.gov/pubmed/9305652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.16.5113 |
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