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Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein.

The expression and incorporation of retroviral enzymes into virions in the form of Gag/Pol precursor polyproteins is believed to be important for the assembly of infectious viral particles. HIV-1 encodes a 160 kDa Gag/Pol precursor that includes Gag, protease (PR), reverse transcriptase (RT) and int...

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Autori principali: Wu, X, Liu, H, Xiao, H, Conway, J A, Hunter, E, Kappes, J C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170145/
https://ncbi.nlm.nih.gov/pubmed/9305652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.16.5113
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