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Mitotic phosphorylation of rab4 prevents binding to a specific receptor on endosome membranes.

Phosphorylation of the monomeric GTPase rab4 in mitotic cells leads to its relocalization from endosome membranes to the cytosol. To determine the mechanism underlying this change in distribution, we established an in vitro assay that reconstituted specific binding of rab4 when endosome-containing m...

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Autori principali: Ayad, N, Hull, M, Mellman, I
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170076/
https://ncbi.nlm.nih.gov/pubmed/9303294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.15.4497
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