A carregar...
Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers.
The V regions of immunoglobulin kappa transgenes are targets for hypermutation in germinal centre B cells. We show by use of modified transgenes that the recruitment of hypermutation is substantially impaired by deletion of the nuclear matrix attachment region (MAR) which flanks the intron-enhancer...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170022/ https://ncbi.nlm.nih.gov/pubmed/9233808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.13.3987 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|