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RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs

BACKGROUND: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein's function than paralogous sequences (that diverged by gene duplication). The utility of phylogenetic information in...

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Bibliografski detalji
Glavni autori: Zmasek, Christian M, Eddy, Sean R
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC116988/
https://ncbi.nlm.nih.gov/pubmed/12028595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-3-14
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