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Near-simultaneous DNA cleavage by the subunits of the junction-resolving enzyme T4 endonuclease VII.

In common with a number of other DNA junction-resolving enzymes, endonuclease VII of bacteriophage T4 binds to a four-way DNA junction as a dimer, and cleaves two strands of the junction. We have used a supercoil-stabilized cruciform substrate to probe the simultaneity of cleavage at the two sites....

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Detalhes bibliográficos
Main Authors: Giraud-Panis, M J, Lilley, D M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169852/
https://ncbi.nlm.nih.gov/pubmed/9171365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2528
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