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Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay.
Expression of many proto-oncogenes, cytokines and lymphokines is regulated by targeting their messenger RNAs for rapid degradation. Essential signals for this control are AU-rich elements (AREs) in the 3' untranslated region (UTR) of these messages. The ARE is loosely defined as the five-nucleo...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1997
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169815/ https://ncbi.nlm.nih.gov/pubmed/9155038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.8.2130 |
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