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The RuvC protein dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts.

The Escherichia coli RuvC protein resolves DNA intermediates produced during genetic recombination. In vitro, RuvC binds specifically to Holliday junctions and resolves them by the introduction of nicks into two strands of like polarity. In contrast to junction recognition, which occurs without rega...

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Bibliografski detalji
Glavni autori: Shah, R, Cosstick, R, West, S C
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169743/
https://ncbi.nlm.nih.gov/pubmed/9135161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.6.1464
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