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The RuvC protein dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts.
The Escherichia coli RuvC protein resolves DNA intermediates produced during genetic recombination. In vitro, RuvC binds specifically to Holliday junctions and resolves them by the introduction of nicks into two strands of like polarity. In contrast to junction recognition, which occurs without rega...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169743/ https://ncbi.nlm.nih.gov/pubmed/9135161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.6.1464 |
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