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The G2/M DNA damage checkpoint inhibits mitosis through Tyr15 phosphorylation of p34cdc2 in Aspergillus nidulans.

It is possible to cause G2 arrest in Aspergillus nidulans by inactivating either p34cdc2 or NIMA. We therefore investigated the negative control of these two mitosis-promoting kinases after DNA damage. DNA damage caused rapid Tyr15 phosphorylation of p34cdc2 and transient cell cycle arrest but had l...

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Detalhes bibliográficos
Main Authors: Ye, X S, Fincher, R R, Tang, A, Osmani, S A
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169625/
https://ncbi.nlm.nih.gov/pubmed/9009279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.1.182
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