The G2/M DNA damage checkpoint inhibits mitosis through Tyr15 phosphorylation of p34cdc2 in Aspergillus nidulans.

It is possible to cause G2 arrest in Aspergillus nidulans by inactivating either p34cdc2 or NIMA. We therefore investigated the negative control of these two mitosis-promoting kinases after DNA damage. DNA damage caused rapid Tyr15 phosphorylation of p34cdc2 and transient cell cycle arrest but had l...

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Bibliographic Details
Main Authors: Ye, X S, Fincher, R R, Tang, A, Osmani, S A
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169625/
https://ncbi.nlm.nih.gov/pubmed/9009279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.1.182
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