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Identification of Phthiodiolone Ketoreductase, an Enzyme Required for Production of Mycobacterial Diacyl Phthiocerol Virulence Factors

Diacyl phthiocerol esters and their congeners are mycobacterial virulence factors. The biosynthesis of these complex lipids remains poorly understood. Insight into their biosynthesis will aid the development of rationally designed drugs that inhibit their production. In this study, we investigate a...

詳細記述

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書誌詳細
主要な著者: Onwueme, Kenolisa C., Vos, Cheryl J., Zurita, Juan, Soll, Clifford E., Quadri, Luis E. N.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169502/
https://ncbi.nlm.nih.gov/pubmed/15995190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.14.4760-4766.2005
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