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Identification of Phthiodiolone Ketoreductase, an Enzyme Required for Production of Mycobacterial Diacyl Phthiocerol Virulence Factors

Diacyl phthiocerol esters and their congeners are mycobacterial virulence factors. The biosynthesis of these complex lipids remains poorly understood. Insight into their biosynthesis will aid the development of rationally designed drugs that inhibit their production. In this study, we investigate a...

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Bibliografische gegevens
Hoofdauteurs: Onwueme, Kenolisa C., Vos, Cheryl J., Zurita, Juan, Soll, Clifford E., Quadri, Luis E. N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169502/
https://ncbi.nlm.nih.gov/pubmed/15995190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.14.4760-4766.2005
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