Multiple Roles of Vertebrate REV Genes in DNA Repair and Recombination

In yeast, Rev1, Rev3, and Rev7 are involved in translesion synthesis over various kinds of DNA damage and spontaneous and UV-induced mutagenesis. Here, we disrupted Rev1, Rev3, and Rev7 in the chicken B-lymphocyte line DT40. REV1(−)(/)(−) REV3(−)(/)(−) REV7(−)(/)(−) cells showed spontaneous cell dea...

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Bibliografski detalji
Glavni autori: Okada, Takashi, Sonoda, Eiichiro, Yoshimura, Michio, Kawano, Yoshiaki, Saya, Hideyuki, Kohzaki, Masaoki, Takeda, Shunichi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Chromosome Structure and Dynamics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168817/
https://ncbi.nlm.nih.gov/pubmed/15988022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.14.6103-6111.2005
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