Multiple Roles of Vertebrate REV Genes in DNA Repair and Recombination

In yeast, Rev1, Rev3, and Rev7 are involved in translesion synthesis over various kinds of DNA damage and spontaneous and UV-induced mutagenesis. Here, we disrupted Rev1, Rev3, and Rev7 in the chicken B-lymphocyte line DT40. REV1(−)(/)(−) REV3(−)(/)(−) REV7(−)(/)(−) cells showed spontaneous cell dea...

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Detalhes bibliográficos
Main Authors: Okada, Takashi, Sonoda, Eiichiro, Yoshimura, Michio, Kawano, Yoshiaki, Saya, Hideyuki, Kohzaki, Masaoki, Takeda, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168817/
https://ncbi.nlm.nih.gov/pubmed/15988022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.14.6103-6111.2005
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