Myc Stimulates Nuclearly Encoded Mitochondrial Genes and Mitochondrial Biogenesis

Although several genes involved in mitochondrial function are direct Myc targets, the role of Myc in mitochondrial biogenesis has not been directly established. We determined the effects of ectopic Myc expression or the loss of Myc on mitochondrial biogenesis. Induction of Myc in P493-6 cells result...

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Autors principals: Li, Feng, Wang, Yunyue, Zeller, Karen I., Potter, James J., Wonsey, Diane R., O'Donnell, Kathryn A., Kim, Jung-whan, Yustein, Jason T., Lee, Linda A., Dang, Chi V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168798/
https://ncbi.nlm.nih.gov/pubmed/15988031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.14.6225-6234.2005
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