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High Incidence of Scrapie Induced by Repeated Injections of Subinfectious Prion Doses

To clarify the mechanisms leading to the development of Creutzfeldt-Jakob disease in some recipients of pituitary-derived human growth hormone (hGH), we investigated the effects of repeated injections of low prion doses in mice. The injections were performed, as in hGH-treated children, by a periphe...

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Main Authors: Jacquemot, Catherine, Cuche, Céline, Dormont, Dominique, Lazarini, Françoise
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168769/
https://ncbi.nlm.nih.gov/pubmed/15994784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8904-8908.2005
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