In Vitro and In Vivo Bactericidal Activities of Vancomycin Dispersed in Porous Biodegradable Poly(ɛ-Caprolactone) Microparticles

Treatment of methicillin-resistant Staphylococcus aureus osteomyelitis requires a prolonged antibiotic therapy with vancomycin. Because of its weak diffusion, the in situ implantation of vancomycin could be interesting. The activity of vancomycin encapsulated in microparticles was evaluated in vitro...

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Hlavní autoři: Le Ray, Anne-Marie, Gautier, Hélène, Laty, Marie-Katel, Daculsi, Guy, Merle, Christian, Jacqueline, Cédric, Hamel, Antoine, Caillon, Jocelyne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168678/
https://ncbi.nlm.nih.gov/pubmed/15980391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.3025-3027.2005
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