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Innate Immune Defense against Pneumococcal Pneumonia Requires Pulmonary Complement Component C3

Complement is known to be involved in protection against systemic infection with Streptococcus pneumoniae. However, less is known about effects of complement within the lungs during pneumococcal pneumonia. By intranasally infecting transgenic mice unable to express complement C3, we investigated the...

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Autors principals: Kerr, Alison R., Paterson, Gavin K., Riboldi-Tunnicliffe, Alan, Mitchell, Tim J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168602/
https://ncbi.nlm.nih.gov/pubmed/15972516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.4245-4252.2005
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