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Posttranslational Modification of Recombinant Plasmodium falciparum Apical Membrane Antigen 1: Impact on Functional Immune Responses to a Malaria Vaccine Candidate

Recombinant apical membrane antigen 1 (AMA1) is a leading vaccine candidate for Plasmodium falciparum malaria, as antibodies against recombinant P. falciparum AMA1 (PfAMA1) interrupt merozoite invasion into erythrocytes. In order to investigate the role of posttranslational modification in modulatin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Giersing, Birgitte, Miura, Kazutoyo, Shimp, Richard, Wang, Jin, Zhou, Hong, Orcutt, Andrew, Stowers, Anthony, Saul, Allan, Miller, Louis H., Long, Carole, Singh, Sanjay
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168543/
https://ncbi.nlm.nih.gov/pubmed/15972483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.3963-3970.2005
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