Posttranslational Modification of Recombinant Plasmodium falciparum Apical Membrane Antigen 1: Impact on Functional Immune Responses to a Malaria Vaccine Candidate

Recombinant apical membrane antigen 1 (AMA1) is a leading vaccine candidate for Plasmodium falciparum malaria, as antibodies against recombinant P. falciparum AMA1 (PfAMA1) interrupt merozoite invasion into erythrocytes. In order to investigate the role of posttranslational modification in modulatin...

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Detalhes bibliográficos
Main Authors: Giersing, Birgitte, Miura, Kazutoyo, Shimp, Richard, Wang, Jin, Zhou, Hong, Orcutt, Andrew, Stowers, Anthony, Saul, Allan, Miller, Louis H., Long, Carole, Singh, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168543/
https://ncbi.nlm.nih.gov/pubmed/15972483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.3963-3970.2005
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