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IFN-γ-induced immune adaptation of the proteasome system is an accelerated and transient response
Peptide generation by the proteasome is rate-limiting in MHC class I-restricted antigen presentation in response to IFN-γ. IFN-γ-induced de novo formation of immunoproteasomes, therefore, essentially supports the rapid adjustment of the mammalian immune system. Here, we report that the molecular int...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1166598/ https://ncbi.nlm.nih.gov/pubmed/15944226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501711102 |
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