Isolation and Characterization of a sigB Deletion Mutant of Staphylococcus aureus

The sigB gene of Staphylococcus aureus, coding for the alternate sigma factor B, has been deleted by allelic replacement mutagenesis. The mutant grew as well as the parent in vitro, although it was deficient in clumping factor, coagulase, and pigment. In two murine and one rat infection model the mu...

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izdano v:	Infect Immun
Principais autores:	Nicholas, R. O., Li, Tong, McDevitt, D., Marra, Andrea, Sucoloski, S., Demarsh, P. L., Gentry, D. R.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1999
Teme:	Molecular and Cellular Pathogenesis
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.7.3667-3669.1999
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