Isolation and Characterization of a sigB Deletion Mutant of Staphylococcus aureus

The sigB gene of Staphylococcus aureus, coding for the alternate sigma factor B, has been deleted by allelic replacement mutagenesis. The mutant grew as well as the parent in vitro, although it was deficient in clumping factor, coagulase, and pigment. In two murine and one rat infection model the mu...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Nicholas, R. O., Li, Tong, McDevitt, D., Marra, Andrea, Sucoloski, S., Demarsh, P. L., Gentry, D. R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.7.3667-3669.1999
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