Isolation and Characterization of a sigB Deletion Mutant of Staphylococcus aureus

The sigB gene of Staphylococcus aureus, coding for the alternate sigma factor B, has been deleted by allelic replacement mutagenesis. The mutant grew as well as the parent in vitro, although it was deficient in clumping factor, coagulase, and pigment. In two murine and one rat infection model the mu...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Nicholas, R. O., Li, Tong, McDevitt, D., Marra, Andrea, Sucoloski, S., Demarsh, P. L., Gentry, D. R.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1999
Subjects:	Molecular and Cellular Pathogenesis
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.7.3667-3669.1999
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