Cytotoxic T-Lymphocyte Epitopes Fused to Anthrax Toxin Induce Protective Antiviral Immunity

We have investigated the use of the protective antigen (PA) and lethal factor (LF) components of anthrax toxin as a system for in vivo delivery of cytotoxic T-lymphocyte (CTL) epitopes. During intoxication, PA directs the translocation of LF into the cytoplasm of mammalian cells. Here we demonstrate...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Doling, Amy M., Ballard, Jimmy D., Shen, Hao, Krishna, Kaja Murali, Ahmed, Rafi, Collier, R. John, Starnbach, Michael N.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.7.3290-3296.1999
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