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Cytotoxic T-Lymphocyte Epitopes Fused to Anthrax Toxin Induce Protective Antiviral Immunity

We have investigated the use of the protective antigen (PA) and lethal factor (LF) components of anthrax toxin as a system for in vivo delivery of cytotoxic T-lymphocyte (CTL) epitopes. During intoxication, PA directs the translocation of LF into the cytoplasm of mammalian cells. Here we demonstrate...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Doling, Amy M., Ballard, Jimmy D., Shen, Hao, Krishna, Kaja Murali, Ahmed, Rafi, Collier, R. John, Starnbach, Michael N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116508/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377103/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.7.3290-3296.1999
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