Cytotoxic T-Lymphocyte Epitopes Fused to Anthrax Toxin Induce Protective Antiviral Immunity

We have investigated the use of the protective antigen (PA) and lethal factor (LF) components of anthrax toxin as a system for in vivo delivery of cytotoxic T-lymphocyte (CTL) epitopes. During intoxication, PA directs the translocation of LF into the cytoplasm of mammalian cells. Here we demonstrate...

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Hlavní autoři: Doling, Amy M., Ballard, Jimmy D., Shen, Hao, Krishna, Kaja Murali, Ahmed, Rafi, Collier, R. John, Starnbach, Michael N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC116508/
https://ncbi.nlm.nih.gov/pubmed/10377103
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