Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) has a major impact on the regulation of the folic acid pathway due to conversion of 5,10-methylenetetrahydrofolate (methylene-THF) to 5-methyl-THF. Two common polymorphisms (677C>T and 1298A>C) in the gene coding for MTHFR have been shown...

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Main Authors: Schnakenberg, Eckart, Mehles, Andrea, Cario, Gunnar, Rehe, Klaus, Seidemann, Kathrin, Schlegelberger, Brigitte, Elsner, Holger A, Welte, Karl H, Schrappe, Martin, Stanulla, Martin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2005
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1164414/
https://ncbi.nlm.nih.gov/pubmed/15921520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-6-23
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