Novel Transcriptional Regulatory Signals in the Adeno-Associated Virus Terminal Repeat A/D Junction Element

Adeno-associated virus (AAV) type 2 vectors transfer stable, long-term gene expression to diverse cell types in vivo. Many gene therapy applications require the control of long-term transgene expression, and AAV vectors, similar to other gene transfer systems, are being evaluated for delivery of reg...

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Main Authors: Haberman, Rebecca P., McCown, Thomas J., Samulski, Richard Jude
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Gene Therapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC116385/
https://ncbi.nlm.nih.gov/pubmed/10954575
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