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Direct Ex Vivo Kinetic and Phenotypic Analyses of CD8(+) T-Cell Responses Induced by DNA Immunization

CD8(+) T-cell responses can be induced by DNA immunization, but little is known about the kinetics of these responses in vivo in the absence of restimulation or how soon protective immunity is conferred by a DNA vaccine. It is also unclear if CD8(+) T cells primed by DNA vaccines express the vigorou...

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Detalhes bibliográficos
Main Authors: Hassett, Daniel E., Slifka, Mark K., Zhang, Jie, Whitton, J. Lindsay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116337/
https://ncbi.nlm.nih.gov/pubmed/10954526
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