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Probing the active site of glyoxalase I from human erythrocytes by use of the strong reversible inhibitor S-p-bromobenzylglutathione and metal substitutions

Glyoxalase I from human erythrocytes was studied by use of the strong reversible competitive inhibitor S-p-bromobenzylglutathione. Replacements of cobalt, manganese and magnesium for the essential zinc in the enzyme were made by a new procedure involving 10% methanol as a stabilizer of the enzyme. T...

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Detalhes bibliográficos
Main Authors: Aronsson, Anne-Charlotte, Sellin, Siv, Tibbelin, Gudrun, Mannervik, Bengt
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163055/
https://ncbi.nlm.nih.gov/pubmed/7317034
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