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Interaction of pseudomonic acid A with Escherichia coli B isoleucyl-tRNA synthetase.

Sodium pseudomonate was shown to be a powerful competitive inhibitor of Escherichia coli B isoleucyl-tRNA synthetase (Ile-tRNA synthetase). The antibiotic competitively inhibits (Ki 6 nM; cf. Km 6.3 microM), with respect top isoleucine, the formation of the enzyme . Ile approximately AMP complex as...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Hughes, J, Mellows, G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1980
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1162199/
https://ncbi.nlm.nih.gov/pubmed/6258580
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