Activation of NFAT-Dependent Gene Expression by Nef: Conservation among Divergent Nef Alleles, Dependence on SH3 Binding and Membrane Association, and Cooperation with Protein Kinase C-θ

Here we show that the potential to regulate NFAT is a conserved property of different Nef alleles and that Nef residues involved in membrane targeting and SH3 binding are critical for this function. Cotransfection of an activated protein kinase C-θ (PKC-θ) with Nef implicated PKC-θ as a possible phy...

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Detaylı Bibliyografya
Asıl Yazarlar: Manninen, Aki, Huotari, Päivi, Hiipakka, Marita, Renkema, G. Herma, Saksela, Kalle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Virus-Cell Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC115932/
https://ncbi.nlm.nih.gov/pubmed/11222731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.3034-3037.2001
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