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HIF-1α: a master regulator of innate host defenses?

In the days following infection, when the human body develops and refines antibodies and prepares to mount an adaptive immune response, the bulwark of innate host defense against microbial infection is the polymorphonuclear leukocyte (PMN). PMNs seek out, identify, engulf, and sterilize invading mic...

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Autori principali: Zarember, Kol A., Malech, Harry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159156/
https://ncbi.nlm.nih.gov/pubmed/16007247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25740
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