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Enhanced microarray performance using low complexity representations of the transcriptome

Low abundance mRNAs are more difficult to examine using microarrays than high abundance mRNAs due to the effect of concentration on hybridization kinetics and signal-to-noise ratios. This report describes the use of low complexity representations (LCRs) of mRNA as the targets for cDNA microarrays. I...

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Detalhes bibliográficos
Principais autores: Rondeau, Gaëlle, McClelland, Michael, Nguyen, Toan, Risques, Rosana, Wang, Yipeng, Judex, Martin, Cho, Ann H., Welsh, John
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159120/
https://ncbi.nlm.nih.gov/pubmed/15987785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni095
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