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Increased Expression of MIP-1α and MIP-1β mRNAs in the Brain Correlates Spatially and Temporally with the Spongiform Neurodegeneration Induced by a Murine Oncornavirus

The chimeric murine oncornavirus FrCas(E) causes a rapidly progressive paralytic disease associated with spongiform neurodegeneration throughout the neuroaxis. Neurovirulence is determined by the sequence of the viral envelope gene and by the capacity of the virus to infect microglia. The neurocytop...

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Pubblicato in:J Virol
Autori principali: Askovic, Srdjan, Favara, Cynthia, McAtee, Frank J., Portis, John L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2001
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115891/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11222690/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.6.2665-2674.2001
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