Increased Expression of MIP-1α and MIP-1β mRNAs in the Brain Correlates Spatially and Temporally with the Spongiform Neurodegeneration Induced by a Murine Oncornavirus

The chimeric murine oncornavirus FrCas(E) causes a rapidly progressive paralytic disease associated with spongiform neurodegeneration throughout the neuroaxis. Neurovirulence is determined by the sequence of the viral envelope gene and by the capacity of the virus to infect microglia. The neurocytop...

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Bibliographic Details
Main Authors:	Askovic, Srdjan, Favara, Cynthia, McAtee, Frank J., Portis, John L.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 2001
Subjects:	Pathogenesis and Immunity
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC115891/ https://ncbi.nlm.nih.gov/pubmed/11222690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.2665-2674.2001
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Increased Expression of MIP-1α and MIP-1β mRNAs in the Brain Correlates Spatially and Temporally with the Spongiform Neurodegeneration Induced by a Murine Oncornavirus

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