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Increased Expression of MIP-1α and MIP-1β mRNAs in the Brain Correlates Spatially and Temporally with the Spongiform Neurodegeneration Induced by a Murine Oncornavirus

The chimeric murine oncornavirus FrCas(E) causes a rapidly progressive paralytic disease associated with spongiform neurodegeneration throughout the neuroaxis. Neurovirulence is determined by the sequence of the viral envelope gene and by the capacity of the virus to infect microglia. The neurocytop...

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Detalhes bibliográficos
Main Authors: Askovic, Srdjan, Favara, Cynthia, McAtee, Frank J., Portis, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115891/
https://ncbi.nlm.nih.gov/pubmed/11222690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.2665-2674.2001
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