Increased Expression of MIP-1α and MIP-1β mRNAs in the Brain Correlates Spatially and Temporally with the Spongiform Neurodegeneration Induced by a Murine Oncornavirus

The chimeric murine oncornavirus FrCas(E) causes a rapidly progressive paralytic disease associated with spongiform neurodegeneration throughout the neuroaxis. Neurovirulence is determined by the sequence of the viral envelope gene and by the capacity of the virus to infect microglia. The neurocytop...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Askovic, Srdjan, Favara, Cynthia, McAtee, Frank J., Portis, John L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115891/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11222690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.6.2665-2674.2001
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