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A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers
There has been much speculation regarding the functional relevance of G protein-coupled receptor heterodimers, primarily because demonstrating their existence in vivo has proven to be a considerable challenge. Here we show that the opioid agonist ligand 6′-guanidinonaltrindole (6′-GNTI) has the uniq...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1157030/ https://ncbi.nlm.nih.gov/pubmed/15932946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501112102 |
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