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A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers
There has been much speculation regarding the functional relevance of G protein-coupled receptor heterodimers, primarily because demonstrating their existence in vivo has proven to be a considerable challenge. Here we show that the opioid agonist ligand 6′-guanidinonaltrindole (6′-GNTI) has the uniq...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1157030/ https://ncbi.nlm.nih.gov/pubmed/15932946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501112102 |
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