Functional Analysis of the Roles of Posttranslational Modifications at the p53 C Terminus in Regulating p53 Stability and Activity

Posttranslational modification of the tumor suppressor p53 plays important roles in regulating its stability and activity. Six lysine residues at the p53 C terminus can be posttranslationally modified by various mechanisms, including acetylation, ubiquitination, neddylation, methylation, and sumoyla...

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Bibliografische gegevens
Hoofdauteurs: Feng, Lijin, Lin, Tongxiang, Uranishi, Hiroaki, Gu, Wei, Xu, Yang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Signal Transduction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157004/
https://ncbi.nlm.nih.gov/pubmed/15964796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5389-5395.2005
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