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Akt/Protein Kinase B-Dependent Phosphorylation and Inactivation of WEE1Hu Promote Cell Cycle Progression at G(2)/M Transition
The serine/threonine kinase Akt is known to promote cell growth by regulating the cell cycle in G(1) phase through activation of cyclin/Cdk kinases and inactivation of Cdk inhibitors. However, how the G(2)/M phase is regulated by Akt remains unclear. Here, we show that Akt counteracts the function o...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1156994/ https://ncbi.nlm.nih.gov/pubmed/15964826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5725-5737.2005 |
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