Aryl Hydrocarbon Receptor-Mediated Transcription: Ligand-Dependent Recruitment of Estrogen Receptor α to 2,3,7,8-Tetrachlorodibenzo- p-Dioxin-Responsive Promoters

Using chromatin immunoprecipitation assays, we studied the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated recruitment of the aryl hydrocarbon receptor (AhR) and several coregulators to the CYP1A1 promoter. AhR displayed a time-dependent recruitment, reaching a peak at 75 min and maintaining pro...

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Detalhes bibliográficos
Main Authors: Matthews, Jason, Wihlén, Björn, Thomsen, Jane, Gustafsson, Jan-Åke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156992/
https://ncbi.nlm.nih.gov/pubmed/15964790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5317-5328.2005
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