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Thermolytic CpG-containing DNA oligonucleotides as potential immunotherapeutic prodrugs
A CpG-containing DNA oligonucleotide functionalized with the 2-(N-formyl-N-methyl)aminoethyl thiophosphate protecting group (CpG ODN fma1555) was prepared from phosphoramidites 1a–d using solid-phase techniques. The oligonucleotide behaved as a prodrug by virtue of its conversion to the well-studied...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1156963/ https://ncbi.nlm.nih.gov/pubmed/15972797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki657 |
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