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Minihelix-loop RNAs: minimal structures for aminoacylation catalysts

We report here an in vitro selected ribozyme, KL17, which is active in charging amino acids on its own 5′-OH group. The ribozyme consists of two catalytic domains, one of which (consisting of P5/P6/L6) recognizes amino acid substrates based on the steric environment of the side chain, whereas the ot...

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Hlavní autoři: Ramaswamy, Krishna, Wei, Kenneth, Suga, Hiroaki
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC115283/
https://ncbi.nlm.nih.gov/pubmed/12000836
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