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Flexizyme-catalyzed synthesis of 3′-aminoacyl-NH-tRNAs
Structural analysis of ribosomes in complex with aminoacyl- and/or peptidyl-transfer RNA (tRNA) often suffers from rapid hydrolysis of the ester bond of aminoacyl-tRNAs. To avoid this issue, several methods to introduce an unhydrolyzable amide bond instead of the canonical ester bond have been devel...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6511858/ https://ncbi.nlm.nih.gov/pubmed/30843032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz143 |
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