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Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase
SET8 (also known as PR-SET7) is a histone H4-Lys-20-specific methyltransferase that is implicated in cell-cycle-dependent transcriptional silencing and mitotic regulation in metazoans. Herein we report the crystal structure of human SET8 (hSET8) bound to a histone H4 peptide bearing Lys-20 and the p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1151662/ https://ncbi.nlm.nih.gov/pubmed/15933070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1318405 |
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