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Active-site serine mutants of the Streptomyces albus G beta-lactamase.

By using site-directed mutagenesis, the active-site serine residue of the Streptomyces albus G beta-lactamase was substituted by alanine and cysteine. Both mutant enzymes were produced in Streptomyces lividans and purified to homogeneity. The cysteine beta-lactamase exhibited a substrate-specificity...

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Hlavní autoři: Jacob, F, Joris, B, Frère, J M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151291/
https://ncbi.nlm.nih.gov/pubmed/1908220
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