Polyglutamine-expanded spinocerebellar ataxia-7 protein disrupts normal SAGA and SLIK histone acetyltransferase activity

Histone acetyltransferases have been shown to participate in many essential cellular processes, particularly those associated with activation of transcription. SAGA (Spt-Ada-Gcn5 acetyltransferase) and SLIK (SAGA-like) are two highly homologous multisubunit histone acetyltransferase complexes that w...

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Bibliografische gegevens
Hoofdauteurs: McMahon, Stacey J., Pray-Grant, Marilyn G., Schieltz, David, Yates, John R., Grant, Patrick A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2005
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150861/
https://ncbi.nlm.nih.gov/pubmed/15932941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503493102
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