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Gene expression patterns define key transcriptional events in cell-cycle regulation by cAMP and protein kinase A

Although a substantial number of hormones and drugs increase cellular cAMP levels, the global impact of cAMP and its major effector mechanism, protein kinase A (PKA), on gene expression is not known. Here we show that treatment of murine wild-type S49 lymphoma cells for 24 h with 8-(4-chlorophenylth...

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Main Authors: Zambon, Alexander C., Zhang, Lingzhi, Minovitsky, Simon, Kanter, Joan R., Prabhakar, Shyam, Salomonis, Nathan, Vranizan, Karen, Dubchak, Inna, Conklin, Bruce R., Insel, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150853/
https://ncbi.nlm.nih.gov/pubmed/15939874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503363102
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