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Global and Hox-specific roles for the MLL1 methyltransferase
The mixed-lineage leukemia (MLL1/ALL-1/HRX) histone methyltransferase is involved in the epigenetic maintenance of transcriptional memory and the pathogenesis of human leukemias. To understand its role in cell type specification, we determined the human genomic binding sites of MLL1. We found that M...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150839/ https://ncbi.nlm.nih.gov/pubmed/15941828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503072102 |
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